- Executive Associate Dean of the Texas A&M University College of Engineering
- Associate Agency Director of the Texas A&M Engineering Experiment Station
- Professor, Chemical Engineering
- Presidential Impact Fellow
- Ray B. Nesbitt Endowed Chair
- Affiliated Faculty, Biomedical Engineering
- Phone: 979-845-1321
- FAX: 979-845-6446
- Email: arulj@tamu.edu
- Office: Zachry Engineering Education Complex, Suite 500
Educational Background
- Ph.D., University of California, Irvine – 1998
- M.S., Tufts University – 1994
- B.S., Birla Institute of Technology & Science – 1987
Research Interests
-
- Molecular systems biotechnology, specifically on using integrated experimental and modeling approaches for investigating problems in human health and medicine
- Systems biology of cytokine signaling in inflammatory diseases
- Inter-kingdom signaling interactions between bacteria and human cells in GI tract infections
- Development of microfluidic model systems for combinatorial drug screening and vascular tissue engineering
Awards & Honors
- 2017 Texas A&M Presidential Impact Fellow
- 2017 Texas Engineering Experiment Station Select Fellow
- 2016 Holder of the Ray Nesbitt Chair
- 2015 Fellow, American Institute of Medical and Biological Engineering (AIMBE)
- 2015 Engineering Genesis Award, Texas A&M Engineering Experiment Station
- 2014 Association of Former Students Distinguished Achievement Award in Teaching
- 2014 Outstanding Service Award, Department of Chemical Engineering
- 2013 Tenneco Meritorious Teaching Award
- 2011 Celanese Teaching Excellence Award
- 2010 TEES Select Young Faculty
- 2009 NSF CAREER award
Selected Publications
- Yang J, Chawla R, Rhee KY, Gupta R, Manson MD, Jayaraman A#, Lele P#. Biphasic chemotaxis of E. coli to the microbiota metabolite indole. Proceedings of the National Academy of Sciences. 2020. #: Corresponding authors
- Lei, M, Menon R, Manteiga S, Alden S, Hunt C, Alaniz RC, Lee K#, Jayaraman A#. Environmental chemical diethylhexyl phthalate alters intestinal microbiota community structure and metabolite profile in mice. mSystems 2019. #: Corresponding authors
- DeLuca JAA, Allred KF, Menon R, Riordan R, Weeks B, Jayaraman A, Allred CD. Bispheno-A alters microbiota metabolites derived from aromatic amino acids and worsens activity during colitis. Experimental Biology and Medicine. 2019.
- Krishnan S, Ding Y, Saedi N, Choi M, Sridharan GV, Sherr, DH, Yarmush ML, Alaniz RC, Jayaraman A#, Lee K#. Gut microbiota-derived tryptophan metabolites modulate inflammatory response in hepatocytes and macrophages. Cell Reports. 2018. #: Joint corresponding authors
- Sule N, Pasupuleti S, Kohli N, Menon R, Dangott L, Manson MD, Jayaraman A. The norepinephrine metabolite 3,4-dihydroxymandelic acid is produced by the commensal microbiota and promotes chemotaxis and virulence gene expression in enterohemorrhagic Escherichia coli. Infection & Immunity. 2017
- Pasupuleti S, Sule N, Manson MD, Jayaraman A. Conversion of the norepinephrine to 3,4-dihydroxymandelic acid in Escherichia coli requires the QseBC quorum sensing system and the FeaR transcription factor. Journal of Bacteriology. 2017. 200(1).
- Sridharan, G. V., Choi, K. O., Klemashevich, C., Wu, C., Prabhakaran, D., Pan, L., Steinmeyeter, S., Mueller, C., Yousofshahi, M., Alaniz, R. C., Lee, K#. and Jayaraman, A#. “Prediction and quantification of bioactive microbiota metabolites in the mouse gut”. Nature Communications. 2014. #: Joint corresponding authors