- Director of Graduate Studies, Chemical Engineering
- Associate Professor, Chemical Engineering
- Phone: 979-862-1454
- FAX: 979-845-6446
- Email: hjwu@tamu.edu
- Office: CHEN 227
- Website: Research Website
Educational Background
- Ph.D., Texas A&M University
- M.S., National Cheng Kung University, Taiwan
- B.S., National Cheng Kung University, Taiwan
Research Interests
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- Development of diagnostic techniques for medical applications using nanostructured materials
- Analytical tools for medical diagnostics
- Influence of multivalency on pathogen-host cell recognition
- Impact of cell membrane environment on pathogen-host interactions
- Applications in infectious disease screening
- Exploration of cell membrane function
- Targeted drug delivery
Awards & Honors
- Kaneka Junior Faculty Award (2016)
Selected Publications
- Krishnan, P., Singla, A., Lee, C.-A, Weatherston, J.D., Worstell, N.C., and Wu, H.-J.*, Hetero-multivalent binding of Cholera Toxin Subunit B with glycolipid mixtures, Colloids and Surfaces B: Biointerfaces, vol. 160, pp. 281-288, [Cover Article], DOI: 10.1016/j.colsurfb.2017.09.035 (2017).
- Liu, C., Zhao, Z. , Fan, J., Lyon, C.J., Wu, H.-J., Nedelkov, D., Zelazny, A.M., Olivier, K.N., Cazares, L.H., Holland, S.M., Graviss, E.A., Hu, Y., Quantification of circulating M. tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring, Proceedings of the National Academy of Sciences, 114 (15) 3969-3974 (2017)
- Weatherston, J.D., Worstell, N.C., Wu, H. -J., Quantitative Surface-Enhanced Raman Spectroscopy (SERS) for Kinetic Analysis of Aldol Condensation Using Ag-Au Core-Shell Nanocube, Analyst, vol. 141, pp. 6051-6060 (2016). DOI: 10.1039/C6AN01098A
- Worstell, D. N., Krishnan, P., Weatherston, D. J., Wu, H. -J., Binding Cooperativity Matters: A GM1-like Ganglioside-Cholera Toxin B Subunit Binding Study Using a Nanocube-Based Lipid Bilayer Array, PLOS ONE , 11(4): e0153265 (2016). DOI:10.1371/journal.pone.0153265
- Iversen, L., Tu, H-.L., Lin, W.-C, Christensen, S.M., Abel, S.M., Iwig, J., Wu, H.-J., Gureasko, J., Yu, C-.H., Rhodes, C., Petit, R. S., Stamou, D., Chakraborty, A.K., Kuriyan, J., Groves, J.T., Ras activation by SOS: Allosteric regulation by altered fluctuation dynamics, vol. 345, pp.50-54, Science. (2014). DOI: 10.1126/science.1250373
- Fan, J., Niu, S., Dong, A., Shi, J., Fine, D., Wu, H.-J., Tian, Y. et al., Nanopore film based enrichment and quantification of low abundance hepcidin from human bodily fluids, Nanomedicine: Nanotechnology, Biology and Medicine, vol. 10, pp. 879-888. (2014) [Cover Article].
- Wu, H.-J., Li, Y., Fan, J., Deng, Z., Zhao, H., Graviss, E. A., Liu, X., Ferrari, M., Ma, X., Hu, Y., Antibody-Free Detection of Mycobacterium tuberculosis Antigen Using Customized Nanotraps, Analytical Chemistry, 86:1988-1996 (2014). DOI: 10.1021/ac4027669
- Wu, H.-J., Henzie, J., Lin, W.-C., Rhodes, C., Li, Z., Thorner, J., Yang, P., Groves, J.T., "Membrane-Protein Binding Measured with Solution-Phase Plasmonic Nanocube Sensors," Nature Methods, 9:1189-91 (2012). DOI:10.1038/nmeth.2211