- Assistant Professor, Chemical Engineering
- Phone: 979-845-5571
- Email: xjzhu@tamu.edu
- Office: CHEN 212
- Website: Research Website
Educational Background
- Postdoctoral Associate, Institute for Medical Engineering and Science, Massachusetts Institute of Technology - 2019
- Visiting Postdoctoral Fellow, Wyss Institute - 2019
- Ph.D., Chemical Engineering, University of California, Berkeley - 2017
- B.S., Biosciences (DII), Nanjing University, China - 2012
Research Interests
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- Natural product biosynthesis
- Xenobiotic metabolism
- Biochemistry
- Enzymology
- Microbial systems
- Biomolecular engineering
- Secretion systems
- Synthetic biology
Awards & Honors
- Dean of Engineering Excellence Award (Assistant Professor Level), TEES, 2024
- Engineering Genesis Award, TEES, 2023
- Maximizing Investigators' Research Award for Early Stage Investigators, National Institutes of Health – 2022
- Outstanding Junior Faculty Award, The Artie McFerrin Department of Chemical Engineering – 2022
Selected Publications
- Gordils-Valentin, L., Ouyang, H., Qian, L., Hong, J., Zhu, X.*, Conjugative type IV secretion systems enable bacterial antagonism that operates independently of plasmid transfer. Commun. Biol., 2024, 7, 499.
- Ouyang, H., Xu, Z., Hong, J., Malroy, J., Qian, L., Ji, S., Zhu, X.*, “Mining the Metabolic Capacity of Clostridium sporogenes Aided by Machine Learning”, Angew. Chem., 2024, e202319925.
- Qian, L., Mohanty, P., Jayaraman, A., Mittal, J., Zhu, X.*, “Specific residues and conformational plasticity define the substrate specificity of short-chain dehydrogenases/reductases”, J. Biol. Chem. 2024., 300(1), 105596.
- Qian, L., Ouyang, H., Gordils-Valentin, L., Hong, J., Jayaraman, A.*, Zhu, X.* “Identification of Gut Bacterial Enzymes for Keto-Reductive Metabolism of Xenobiotics” ACS Chem. Biol., 2022, 17(7), 1665–1671.
- Ouyang, H., Hong, J., Malroy, J., Zhu, X.* "An E. coli-Based Biosynthetic Platform Expands the Structural Diversity of Natural Benzoxazoles" ACS Synth. Biol., 2021, 10(9), 2151–2158.